Fall 2023: Phage Hunters Advancing Genomic and Evolutionary Science (BIO-498)
(see below for details)
Spring 2023: Statistical Models for Biology (BIO-415/514)
This lecture and lab course (a core requirement for several graduate programs in the Life Sciences) focuses on the fundamentals of statistics, including probability, descriptive statistics, estimation, hypothesis testing, as well as how to implement statistical models using the software package R.
Fall 2022: Phage Hunters Advancing Genomic and Evolutionary Science (BIO-498)
Spring 2022: Phage Hunters Advancing Genomic and Evolutionary Science (BIO-498)
Fall/Spring 2020/21: Phage Hunters Advancing Genomic and Evolutionary Science (BIO-498)
Fall/Spring 2019/20: Phage Hunters Advancing Genomic and Evolutionary Science (BIO-498)
In 1977, Fred Sanger and his colleagues developed a DNA sequencing technique with which they sequenced the first full genome – that of a bacteria-infecting virus (i.e., a bacteriophage) called ⏀-X174. His pioneering work changed the course of biology & medicine forever.
Now, it is your turn! In this hands-on laboratory course, undergraduate STEM majors actively engage in research to discover, isolate, and computationally analyze bacteriophages. In Fall and Spring, a selection of students will be able to present their results at the BioSci Southwest Symposium and the SEA-PHAGES symposium (held at the Howard Hughes Medical Institute’s Janelia Research Campus, VA), respectively.
Topics – Part I (Phage Discovery):
* Sample collection field trip
* Isolation and purification of phages from the environmental samples
* Amplification of the purified phages
* Isolation of phage genomic DNA
* Restriction digest analyses of genomic DNA samples
* Visualization of phage morphology by electron microscopy
* Preparation and submission of phage DNA for sequencing
Topics – Part II (Bioinformatics):
* Annotate phage genomes
* Evaluate the overall genome structure
* Perform comparative genomic analyses
* Submission to GenBank
SEA-PHAGES has been shown to increase both the accessibility to research experiences for students as well as the persistence of these students in STEM disciplines: An inclusive Research Education Community (iREC)- Impact of the SEA-PHAGES program on research outcomes and student learning.
Spring 2019: The Human Genome (BIO-494/598; EVO-598)
This course focuses on the recent advances in human genetics that led to an improved understanding of the chronology of human evolution as well as the evolutionary inference related to the genetic basis of disease.
Fall 2018: Evolutionary Data Analysis (BIO-494/598; EVO-598)
This course focuses on the dissemination of historic as well as recent scientific literature in the field of evolution and hands-on evolutionary data analyses.
Spring 2018: General Genetics (BIO-340)
This course surveys the fundamental principles of genetics – the study of biological inheritance.